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| 早期青年乳腺癌保留乳房手术预后的Meta分析 | |
| 引用本文： | 李俊,陆云飞. 早期青年乳腺癌保留乳房手术预后的Meta分析[J]. 中华肿瘤防治杂志, 2011, 18(17): 1382-1386 |
| 作者姓名： | 李俊 陆云飞 |
| 作者单位： | 1. 柳州市柳铁中心医院普外科,广西柳州,545007 2. 广西医科大学一附院胃肠腺体外科,广西南宁,530021 |
| 摘 要： | 目的:评价保留乳房手术治疗早期青年乳腺癌的疗效。方法:计算机检索Cochrane Library、PubMed、EMBASE、中国生物医学文献数据库、中国期刊全文数据库和清华同方数据库,并手工检索相关领域其他杂志。纳入比较保留乳房手术与乳房切除手术治疗早期青年乳腺癌的临床对照试验。按照Cochrane系统评价方法,评价纳入研究质量,对同质研究采用RevMan 5.0软件进行Meta分析。结果:按照入选标准,纳入8个研究共1 307例。Meta分析结果显示,与乳房切除术比,远期生存率相似〔比值比(OR)=1.19,95%CI为0.80～1.77,P>0.05〕,远处转移率差异无统计学意义(OR=1.47,95%CI为0.92～2.35,P>0.05),保留乳房术后局部复发率高,OR=1.96,95%CI为1.50～2.56,P<0.05。结论:早期青年乳腺癌患者保留乳房治疗是可行的,以上结论尚需大量高质量的临床对照研究证实。 |
| 关 键 词： | 乳腺肿瘤 青少年 乳房切除术,区段 乳房切除术 预后 Meta分析 |
Meta-analysis of breast conserving and radical mastectomy in early youth breast cancer |
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| LI Jun,LU Yun-fei. Meta-analysis of breast conserving and radical mastectomy in early youth breast cancer[J]. Chinese Journal of Cancer Prevention and Treatment, 2011, 18(17): 1382-1386 | |
| Authors: | LI Jun LU Yun-fei |
| Affiliation: | LI Jun1,LU Yun-fei2 1.Department of General Surgery,Liutie Central Hospital,Liuzhou 545007,P.R.China 2.Department of Gastrointestinal and Gland Surgery,First Affiliated Hospital of Guangxi Medical University,Nanning 530021,P.R.China |
| Abstract: | OBJECTIVE: To assess the efficacy and safety of breast conserving surgery versus radical mastectomy in young woman.METHODS: Randomized controlled trials(RCTs) and non-randomized studies(HCTs)comparing breast conserving with radical mastectomy were identified using a predefined search strategy from Cochrane Library,PubMed,EMBASE,CBM and Wangfang Data.Long-term survival,distant metastasis,and ipsilateral breast local recurrence between the two operations were compared by using the methods provided by the Coch... |
| Keywords: | breast neoplasms adolescence mastectomy segmental prognosis Meta-analysis |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |