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慢性肾炎致慢性肾衰竭患者心衰发生相关危险因素分析
引用本文:张继强,陈卫东,张燕,刘磊,尹晓丽. 慢性肾炎致慢性肾衰竭患者心衰发生相关危险因素分析[J]. 中国中西医结合肾病杂志, 2009, 10(4): 329-332
作者姓名:张继强  陈卫东  张燕  刘磊  尹晓丽
作者单位:1. 蚌坤医学院第一附属医院肾内科,蚌埠,233000
2. 蚌埠医学院第一附属医院心血管科,蚌埠,233000
基金项目:安徽省佳林豪研究基金 
摘    要:
目的:了解慢性肾炎致慢性肾衰竭患者血压、血红蛋白、血清白蛋白、血脂、血肌酐、电解质及尿素氮、胱抑素C、同型半胱氨酸及高敏C反应蛋白等指标与心力衰竭发生之间的关系,分析并探讨相关危险因素。方法:回顾性分析我院343例慢性肾炎致慢性肾衰竭患者心衰发生及其同期血压等指标变化情况,了解其规律及相互关系。结果:(1)343例患者有77例合并发生心衰(22.4%),其中19岁~39岁占20.5%,40岁~59岁占22.8%,〉60岁占33.3%;合并发生心衰多为CKD5期患者(97.4%)。(2)血压、血红蛋白、CO2CP、血肌酐、高敏C反应蛋白在有无心衰发生组存在统计学差异(P〈0.01),其中血压、血肌酐、光抑素C、高敏C反应蛋白等与心衰发生呈负相关(P〈0.05),而年龄、钙磷、血清白蛋白及血脂、尿素氮、同型半胱氨酸组间无统计学差异。结论:慢性肾炎致慢性肾衰竭患者心力衰竭发生率很高,其发生可能与高血压、贫血、酸中毒、血肌酐及微炎症状态等因素有关。

关 键 词:慢性肾炎  慢性肾衰竭  心力衰竭  危险因素

Associated Risk Factors of Heart Failure in Patients with Chronic Renal Failure by Chronic Glomerulonephritis
ZHANG Jiqiang,CHEN Weidong,ZHANG Yan,et al. Associated Risk Factors of Heart Failure in Patients with Chronic Renal Failure by Chronic Glomerulonephritis[J]. Chinese Journal of Integrated Traditional and Western Nephrology, 2009, 10(4): 329-332
Authors:ZHANG Jiqiang  CHEN Weidong  ZHANG Yan  et al
Abstract:
Objective:To investigate the changes of heart failure in patients with chronic renal failure(CRF)by chronic glomerulonephritis(CGN),and analyze the relationship between those changes and blood pressure,hemoglobin,serum albumin and lipid,serum creatinine(Scr),electrolytes,Blood urea nitrogen(BUN),cystatin(CysC),homocysteine(Hcy)and high sensitivity C-reactive protein(HsCRP).Methods:Three hundred and forty-three patients with CRF by CGN were evaluated by symptom and sign,and the levels of blood pressure,hemog...
Keywords:Chronic glomerulonephritis Chronic renal failure Heart failure Risk factors  
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