A method for the measurement of ultra-low amounts of prostaglandins in inflammatory exudates using gas chromatography and mass spectrometry期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

A method for the measurement of ultra-low amounts of prostaglandins in inflammatory exudates using gas chromatography and mass spectrometry

Authors:	B. W. Wilson W. Snedden K. T. Tham D. A. Willoughby

Affiliation:	(1) Mass Spectrometry Department Bartholomew's Close, St., Bartholomew's Hospital, EC. 1 London, England

Abstract:	A GC-MS assay for PGE₂ and PGF₂ has been described. The method is highly specific and sensitive down to the sub-picogram level. The assay has been used to measure the time dependence of PG concentration in carrageenan-induced inflammatory exudates and the results compared with a bioassay. Estimates of the extraction and purification yield of PGs from exudates have also been obtained.

Keywords:
本文献已被 SpringerLink 等数据库收录！