| 先天性白内障与缝隙连接蛋白Cx50 |
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| 引用本文： | 林英,郑建秋,刘平. 先天性白内障与缝隙连接蛋白Cx50[J]. 国际眼科杂志, 2007, 7(6): 1658-1661 |
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| 作者姓名： | 林英 郑建秋 刘平 |
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| 作者单位： | 哈尔滨医科大学附属第一临床医学院附属眼科医院,中国黑龙江省哈尔滨市,150001 |
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| 摘 要： | 约1/3的先天性白内障与遗传有关。随着分子生物学技术的发展,近年来愈来愈多地发现Cx50缝隙连接蛋白与先天性白内障有关,其发病机制还不是很明确。本文通过对与缝隙连接蛋白Cx50相关的先天性白内障分子基础的研究做一综述,以期对缝隙连接蛋白分子结构、作用、致病机制有更深的了解。
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| 关 键 词： | 白内障 先天性 缝隙连接蛋白Cx50 |
| 收稿时间： | 2007-05-28 |
| 修稿时间： | 2007-10-01 |
Congenital cataract and Cx50 |
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| Ying Lin,Jian-Qiu Zheng,Ping Liu. Congenital cataract and Cx50[J]. International Eye Science, 2007, 7(6): 1658-1661 |
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| Authors: | Ying Lin Jian-Qiu Zheng Ping Liu |
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| Abstract: | Nearly one third of the congenital cataract cases are inherited . With the development of molecular biology, more and more research shows that Cx50 is related to congenital cataract without definite pathogenesis. To enrich and deepen our understandings of molecular structure, function and pathogenesis of connexin , this review summarizes the molecular basis of congenital cataract associated with Cx50. |
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| Keywords: | cataract congenital Cx50 |
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