131I—SPECT／CT融合显像对分化型甲状腺癌术后诊断临床价值分析

目的：评价用131I—SPECT／CT融合显像方法对分化型甲状腺癌（DTC）术后患者是否有转移病灶的临床诊断意义。方法：156例DTC术后患者在随诊的不同阶段行常规核医学全身131I平面显像，对所见的异常摄取灶再进行131I—SPECT／CT融合显像，比较这两种显像方法的诊断符合率、灵敏度及特异性。结果：全身131I平面显像发现DTC术后异常摄取灶的阳性率为57．05％（89／156），其中61例有颈部摄取患者中，131I—SPECT／CT融合显像提高了对该区域复发和转移的诊断符合率、灵敏度和特异性，在其余颈部以外区域有摄取灶的28例患者中，131I—SPECT／CT融合显像亦可对颈部以外区域可疑摄取灶做出准确定位及定性诊断。结论：131I—SPECT／CT融合显像与常规核医学平面显像相比，在对DTC术后患者随访时有更高的诊断价值，对DTC术后患者的诊疗决策亦有重要意义。

Clinical values of 131I -SPECT/CT fuse imaging in diagnosis of metastatic focus of differ- entiated thyroid carcinoma after operation

Objective： To evaluate importance of 131I -- SPECT/CT fuse imaging in clinical diagnosis of metastasis focus of differentiated thyroid carcinoma （DTC）after operation. Methods： Total of 156 patients with DTC after operation were examined by routine nuclear medicine 131I whole plane imaging , and abnormal uptake focus that was found in routine plane imaging were examined by 131I - SPECT/CT fuse imaging. Results ： Positive rate of abnormal uptake focus was 57.05% （89/156）in routine nuclear medicine plane imaging , among them 61 patients who intake 131I in cervical area. In 28 patients with 1311 uptaking in cervical area, suspicious uptake focus were made located and qualitative diagnosis accurately by 131I - SPECT/CT fuse imaging. Conclusion： 131I- SPECT/CT fuse imaging has more important diagnostic value than routine nuclear medicine plane imaging for patients with DTC after operation.