丙氨酸氨基转移酶不合格献血者特征分析

目的 分析渭南地区2017—2019年丙氨酸氨基转移酶(ALT)不合格献血者检测结果,提供科学合理的宣传、招募、征询及初筛策略.方法 回顾性分析渭南地区2017—2019年无偿献血人群ALT速率法检测结果,比较不同性别、年龄、职业、文化程度、献血次数献血者,以及不同献血季节的ALT不合格率.分析ALT合并4项输血感染疾...

Characteristics analysis of alanine aminotransferase unqualified blood donors

Objective Analyze the test results of alanine aminotransferase(ALT)unqualified unpaid blood donors in Weinan area from 2017 to 2019 to provide scientific and reasonable publicity,recruitment,consultation and initial screening strategies.Methods Retrospective analysis of ALT test results in unpaid blood donors in Weinan from 2017 to 2019.Compare the ALT failure rate of blood donors with different gender,age,occupation,education level,blood donation frequency,and different blood donation seasons.The results of ALT combined with four infection diseases and the interval distribution of ALT test values in the ALT unqualified blood donors were analyzed.Results Among 120817 cases unpaid blood donors,455 cases of ALT were found to be unqualified,and the unqualified rate of ALT was 0.38%,and the differences of the unqualified rate of ALT in different years was statistically significant(P<0.05).The unqualified rate of ALT in male was higher than that in female,which was highest in 25—<35 years old.The unqualified rate of ALT in workers was the highest,which was the lowest in doctors,the highest in the first quarter.ALT unqualified rate of blood donors with different education levels and times of blood donation showed no statistically significant difference(P>0.05).Among the 455 cases ALT-unqualified unpaid blood donors,the single ALT-unqualified was the most,accounting for 99.34%.Only 1 case of ALT combined with anti-HCV unqualified,2 cases of ALT combined with TP unqualified.The distribution of detection values of ALT-unqualified blood donors was the highest in the range of 50—60 U/L,accounting for 80.00%.Conclusion Among ALT-unqualified unpaid blood donors in Weinan area,non-pathological increase in ALT is the main part,mainly caused by unhealthy living habit.In response to the characteristics of ALT-unqualified people,appropriate measures have been taken in the areas of publicity and recruitment,consultation collection,and ALT detection processes to reduce the rate of ALT-unqualified,save blood resources,reduce blood station operating costs,and stabilize the blood donors.