悬浮红细胞及血浆输注对大量输血手术患者凝血功能的影响

目的 观察悬浮红细胞及血浆输注对大量输血手术患者凝血功能的影响.方法 选取2018年12月至2020年5月该院大量输血手术患者63例,输注悬浮红细胞的31例患者为对照组,输注悬浮红细胞及血浆的32例患者为联合组.比较两组输注前后凝血功能指标[凝血酶原时间(PT)、纤维蛋白原(FIB)、凝血酶时间(TT)、活化部分凝血活...

Effects of suspended red blood cells and plasma transfusion on coagulation function in patients undergoing massive blood transfusion

Objective To observe the effects of suspended red blood cells and plasma transfusion on the coagulation function in the patients undergoing massive blood transfusion.Methods Sixty-three patients undergoing massive blood transfusion operations in this hospital from December 2018 to May 2020 were selected,among them 31 patients with suspended red blood cells served as the control group,and 32 patients with suspended red blood cells and plasma as the combined group.The coagulation function indicators[prothrombin time(PT),fibrinogen(FIB),thrombin time(TT),activated partial thromboplastin time(APTT)],hemorheologic indicators[platelet count(PLT),hemoglobin(Hb),hematocrit(HCT)],hospitalization length and incidence rate of coagulopathy before and after transfusion were compared between the two groups.Results PT,APTT and TT at 24,72 h after infusion in the combined group were shorter than those in the control group,FIB and PLT levels were higher than that in the control group(P<0.05).There was no statistically significant difference in HCT and Hb before infusion and at 24,72 h after infusion between the two groups(P>0.05).There was no statistically significant difference in hospitalization stay and incidence rate of coagulation dysfunction between the two groups(P>0.05).Conclusion The infusion of suspended red blood cells and plasma has little influence on the coagulation function and platelets of patients undergoing massive blood transfusion operations,which conduces to prevent the occurrence of coagulation dysfunction and promote the improvement of prognosis.