31例原发性肝细胞癌患者超声诊断中的各项特征分析

目的：对超声检查中原发性肝细胞癌（HCC）的各项特征进行分析，旨在提高原发性肝癌的早期确诊率。方法选择本院经术后病理证实为HCC的31例患者（A组）和非肝内占位病变的96例患者（B组），对两组患者行彩色多普勒超声及超声造影检查，并对超声诊断中的各项特征采取单因素logistic回归分析，并对具有意义的各项检查特征采取多因素logistic回归分析。结果在单因素logistic回归分析中，病灶范围、病灶边界、病灶数量、病灶后方回声、病灶内部回声及病灶是否存在晕环征、彩色多普勒血流信号分级、能量多普勒、脉冲多普勒频谱、造影剂增强方式、占位病变的造影时间-强度曲线中的峰值强度及肿瘤内彩色血管平均密度等超声特征对HCC的预测存在一定意义，而针对上述超声诊断特征中的多因素logistic回归分析中，晕环征、能量多普勒、造影剂增强方式及肿瘤内彩色血管平均密度因素为HCC发生的独立危险因素。结论在HCC的超声诊断中，晕环征、能量多普勒、造影剂增强方式及肿瘤内彩色血管平均密度具有一定诊断价值，通过logistic回归模型可与其他非HCC肝占位病变进行鉴别诊断。

Analysis on the ultrasonic diagnosis characteristics of 31 cases of primary hepatocellular carcinoma

Objective To improve the diagnosis rate by analyzing the ultrasonic diagnosis characteristics of patients with primary hepatocellular carcinoma （HCC）. Methods 31 patients （group A） who were diagnosed as HCC by postoperative pathological and 96 patients （group B） with non space occupying lesions of liver were selected, all the patients received color Doppler and contrast-enhanced ultrasonography, diagnosis characteristics were analyzed by single factor logistic regression analysis. Results Ultrasonic characteristics of focus range, lesion boundaries, number of lesions, lesions in posterior echo, the existence of halo, color Doppler flow signal classification, Doppler energy, Pulsed Doppler spectrum, contrast enhancement method, total time of peak intensity intensity lesions in the curve and Tumor mean color vessel density was significant to the prediction in single factor logistic regression analysis, characteristics of the existence of halo, Doppler energy, contrast enhancement method, Tumor mean color vessel density was independent risk factors for the occurrence of HCC. Conclusion Ultrasonic characteristics of the existence of halo, Doppler energy, contrast enhancement method, tumor mean color vessel density has a certain diagnostic value, differential diagnosis of HCC and non space occupying lesions of liver can be achieved by logistic regression model.