性别对急性ST段抬高心肌梗死直接经皮冠状动脉介入治疗预后的影响

目的 探讨性别对急性ST段抬高心肌梗死(STEMI)直接经皮冠状动脉介入(PCI)治疗预后的影响.方法 分析比较478例男性和101例女性急性ST段抬高心肌梗死患者的危险因素、冠状动脉造影特点和预后情况.结果 不同年龄段STEMI发病率的性别差异有统计学意叉(P<0.01),女性发病较男性晚10年以上,≥71岁女性发病率升高更明显;女性多合并原发性高血压、2型糖尿病,且2型糖尿病明显高于男性(P<0.01);女性多支病变明显高于男性(P<0.01).女性院内病死率、假性动脉瘤/血肿发生率明显高于男性(P<0.05,P<0.01).结论 直接PCI治疗STEMI女性患者的住院病死率及穿刺血管并发症发生率较男性高.

Influence of sex on the prognosis of acute ST elevated myocardial infarction after primary percutaneous coronary intervention

Objective To study the influence of sex on the prognosis in acute ST elevated myocardial in- farction(STEMI)patients after primary percutaneous coronary intervention(PCI).Methods :The risk factors, coronary angiography and prognosis in 478 males and 101 females with STEMl were compared.Results:Mortality of STEMI was significantly different in different age groups(P<0.01).The attack of the STEMI in women was 10 vears later than that of men(P<0.01),especially in those women whose age was over 71 years oId.The complica- tion ratio of hypertension and type 2 mellitus diabetes was higher in female patients than that in male(P<0.01). More multi-vessel lesions were found in female patients than those in male(P<0.01).The incidence of in-hospital mortality,pseudoaneurysm,haematoma Was significantly higher in females than in males(P<0.05.P<0.01).Con- clusions The in-hospital mortalitv and puncture complications in STEMI female patients treated with primary PCI are higher than male patients.