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HIV(+)与肺结核病人CD4~+、CD8~+变化比较分析
引用本文:韦启后,陈柳军,蒲渝成.HIV(+)与肺结核病人CD4~+、CD8~+变化比较分析[J].右江民族医学院学报,2008,30(4):544-545.
作者姓名:韦启后  陈柳军  蒲渝成
作者单位:1. 广西柳州市疾病预防控制中心,广西,柳州,545001
2. 广西壮族自治区龙潭医院检验科,广西,柳州,545005
摘    要:目的比较HIV(+)患者与肺结核病人的CD4+、CD8+细胞的变化。方法采用流式细胞计数仪检测CD4+、CD8+T淋巴细胞。结果HIV/AIDS与肺结核患者存在以CD4+T淋巴细胞下降为突出表现的细胞免疫受损,HIV/AIDS患者的CD4+细胞降低明显高于肺结核病人(P均<0.01),HIV/AIDS患者的CD8+细胞升高明显高于肺结核病人(P<0.01或0.05)。结论HIV/AIDS患者与肺结核病人都存在着不同程度的CD4+T淋巴细胞异常,CD4+T细胞是HIV/AIDS重要指标;CD4+T细胞对肺结核病人是用来估计机体的免疫状态或是一个指标,但不是一个绝对指标。

关 键 词:HIV/AIDS  结核    CD4+T细胞  CD8+T细胞

The fluctuation of CD4~+,CD8~+:HIV(+) vs pulmonary tuberculosis
WEI Qi-hou,CHEN Liu-jun,PU Yu-cheng.The fluctuation of CD4~+,CD8~+:HIV(+) vs pulmonary tuberculosis[J].Journal of Youjiang Medical College For Nationalities,2008,30(4):544-545.
Authors:WEI Qi-hou  CHEN Liu-jun  PU Yu-cheng
Institution:WEI Qi-hou1,CHEN Liu-jun1,PU Yu-cheng2 (1.Liuzhou Diseases , Prevention Control Centre,Liuzhou,Guangxi 545001,China,2.Department of Medical Laboratory,Longtan Hospital of Guangxi Zhuang Autonomous Region,Guangxi 545005,China)
Abstract:Objective To compare the changes of CD4-positive T-lymphocytes and CD8-positive T-lymphocytes in patients with HIV(+) to patients with pulmonary tuberculosis.Methods A flow cytometry was used to measure the CD4+ and CD8+ counts.Results The prominent immune system injury was the decrease of CD4-positive T-lymphocytes in patients with HIV/AIDS and with pulmonary tuberculosis.The decrease of CD4-positive T-lymphocytes in patients with HIV/AIDS was more significant than those in patients with pulmonary tubercul...
Keywords:HIV/AIDS  tuberculosis  pulmonary  CD4positive T-lymphocytes  CD8-positive T-lymphocytes  
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