颞叶癫痫患者颞叶切除术前后的记忆评估

目的探讨颞叶切除术对颞叶癫痫患者术后记忆功能的影响。方法回顾性分析2012年7月至2013年12月收治的17例颞叶癫痫患者的临床资料,采用成人韦氏量表测量患者颞叶切除术前及术后6个月记忆商（MQ）值。结果术前MQ平均值为（89.94±4.45）,术后6个月为（104.76±4.96）,差异显著（P〈0.05）。术前长时MQ值为（37.53±1.95）,术后为（40.53±1.70）,术后长时记忆改善不明显（P〉0.05）。术前短时记忆MQ值为（46.29±2.43）,术后为（54.94±3.18）;术前瞬时MQ均值为（6.12±1.37）,术后为（9.29±1.00）;术后短时及瞬时MQ均较术前有显著差异（P〈0.05）。EngleⅠ～Ⅱ级15例病人中,术后MQ较术前改善11例,无明显变化4例;EngleⅢ～Ⅳ级2例病人中,MQ值较术前下降1例,无改变1例。结论颞叶切除术可明显改善颞叶癫痫患者术后MQ。

Effects of temporal lobectomy on memorial function in patient with intractable temporal lobe epilepsy

Objective To investigate the effects of temporal lobectomy on memorial function in the patients with intractable temporal lobe epilepsy（ITLE）.Methods The clinical data of 17 patients with ITLE undergoing temporal lobectomy from July, 2012 to December, 2013 were analyzed retrospectively. The memory quotient（MQ） was determined by Wechsler Memory Scale（WMS） before the surgery and 6 months after the surgery in all the patients.Results The overall MQ value [（104.76±4.96） points] was significantly higher than that [（89.94±4.45） points] before the surgery in the patients with ITLE（P〈0.05）. The scores of short-term MQ [（54.94±3.18） points]and immediate-MQ [（9.29±1.00） points] were significantly higher 6 months after the surgery than those [they were（46.29±2.43） and（6.12±1.37） points respectively] before the surgery in the patients（P〈0.05）. The score of long-term MQ [（40.53±1.70） points] was insignificantly higher 6 months after the surgery than that [（37.53±1.95） points] before the surgery in the patients（P〉0.05）.Conclusion The memorial function may be significantly improved by the temporal lobectomy in the patients with ITLE.