2型糖尿病肾病糖化血红蛋白等代谢指标的相关性分析

目的 探讨2型糖尿病肾病糖化血红蛋白(HbA1C)、血脂、收缩压(SBP)之间的相关性,以指导临床医生及早防治.方法 128例2型糖尿病患者按照尿白蛋白排泄率(UAER)分为糖尿病肾病组和非糖尿病肾病组,测定并对比分析两组患者的空腹血糖(FBG)、餐后2小时血糖(2hPG)、HbA1C总胆固醇(TC)、HbA1C甘油三酯(TG)、高密度脂蛋白-胆固醇(HDL-C)、低密度脂蛋白-胆固醇(LDL-C)、SBP.结果 糖尿病肾病组FBG、LDL-C、TG、TC、SBP均高于非糖尿病肾病组(P＜0.01).结论 早期控制血糖、血脂、血压,缩短病程,是防止糖尿病肾病发生发展的关键.

Correlative analysis of some metabolism indexes in type 2 diabetic nephropathy

Objective To investigate the correlation among glycosylated hemoglobin(HbA1C),blood fat and systolic blood pressure(SBP),and to give reference to clinical treatment and early prevention.Methods Some indexes in 128 cases of type 2 diabetes mellitus(DM) were measured and calculated,including fasting blood glucose(FBG),plasma glucose 2 hours after meal,glycosylated hemoglobin,total cholesterol(TC),triglyeride (TG),high density lipoprotein-cholesterin(HDL-C),low density lipoproteincholesterin(LDL-C) and systolic blood pressure(SBP).According to their urinary albumin excretion rate(UAER),the patients were divided into diabetic nephropathy group and non-diabetic nephropathy group and their indexes were analyzed.Results The levels of FBG,glycosylated hemoglobin,LDL-C,TG and SBP in diabetic nephropathy group were significantly higher than those in nondiabetic nephropathy group(P<0.01).Conclusion The control of blood glycose,blood fat,blood pressure,and reduction of the course of disease in early period are essential to prevent the occurrence and aggravation of diabetic nephropathy.