国谈抗肿瘤药配备机构的空间可达性评价研究——以武汉市为例

目的：本研究旨在评估武汉市中心城区国谈抗肿瘤药配备机构的空间可达性水平，为优化药物供应与配置提供经验证据。方法：以武汉市为例，采用基于高斯衰减函数的两步移动搜索法(2-Step Floating Catchment Area, 2SFCA)评估研究区域内各个需求单元在不同交通出行方式下的国谈抗肿瘤药配备机构的可达性，同时运用空间自相关分析和K-means聚类分析识别需求单元可达性的分布态势和分类模式。结果：在驾车或公交出行的情况下，武汉市中心城区各需求单元的配药定点机构的可达性呈现出明显的空间分异特征。江汉区、汉阳区等可达性水平较高且均衡，而青山区和洪山区可达性水平较低且内部存在明显分层。此外，各需求单元呈现显著正相关空间分布，区域内高值集聚与分区内部分化现象并存。结论：武汉市中心城区配药机构可达性整体较高，但存在从核心城区向边缘城区递减的趋势；多数辖区的可达性良好且较为均衡，但少数辖区的可达性较差且存在明显的内部等级分层。

Spatial accessibility of dispensing institutions of national negotiated antineoplastic drugs: A case study of Wuhan, China

Objective: This study aims to evaluate the spatial accessibility (SA) level of Dispensing Institutions of National Negotiated Antineoplastic Drugs (DINNAD) in the central urban area of Wuhan and provide empirical evidence for optimizing drug supply and allocation.Methods: Taking Wuhan as an example, the study adopts the Gaussian based 2-Step Floating Catchment Area (2SFCA) method to evaluate the SA of DINNAD in different modes of transportation for each demand unit in the study area, and to identify SA distribution patterns and classification modes for demand units with Spatial autocorrelation analysis and K-means cluster analysis. Results: In the case of driving or public transportation, the SA of the designated medical institutions for dispensing in each demand unit in the central urban area of Wuhan presents obvious spatial differentiation.A higher SA level is reached in Jianghan District and Hanyang District with a fair balance,while a lower SA level is noticed in Qingshan District and Hongshan District, with an obvious internal stratification. In addition, demand units exhibit a significant positive correlation in spatial distribution patterns together with high-value aggregation and intra-zone differentiation phenomena. Conclusion:The overall SA level of DINNAD in the central urban area of Wuhan is relatively high overall, but there is a trend of decreasing from the core urban area to the peripheral urban areas. The SA inmost administrative areas is good and relatively balanced, but a few administrative areas have poor accessibility and obvious internal hierarchical stratification.