| 甲硝唑乳膏的制备及质量控制 |
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| 引用本文： | 兰顺,荆树汉,叶冬梅,符翠莉. 甲硝唑乳膏的制备及质量控制[J]. 药学实践杂志, 2004, 22(5): 289-290 |
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| 作者姓名： | 兰顺 荆树汉 叶冬梅 符翠莉 |
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| 作者单位： | 广西壮族自治区人民医院,广西,南宁,530021 |
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| 摘 要： | 目的:制备甲硝唑乳膏并建立其质量控制标准。方法:以甲硝唑为主药制备甲硝唑乳膏,采用紫外分光光度法测定甲硝唑乳膏中甲硝唑的含量。结果:甲硝唑的平均回收率为100.2％,RSD为1.7％。结论:该制剂处方及工艺具有生产可行性,其质量控制标准符合《中国药典》要求,含量测定方法简单、快速、准确。
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| 关 键 词： | 甲硝唑 乳膏 质量控制 |
| 文章编号： | 1006-0111(2004)05-0289-02 |
| 收稿时间： | 2004-02-06 |
| 修稿时间： | 2004-02-06 |
Preparation and quality control of metronidazole cream |
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| LAN Shun,JING Shu-han,YE Dong-mei and FU Cui-Ii. Preparation and quality control of metronidazole cream[J]. The Journal of Pharmaceutical Practice, 2004, 22(5): 289-290 |
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| Authors: | LAN Shun JING Shu-han YE Dong-mei FU Cui-Ii |
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| Affiliation: | People's Hospital of Guangxi Zhuangzu Autonomous Region, Nanning 530021, China;People's Hospital of Guangxi Zhuangzu Autonomous Region, Nanning 530021, China;People's Hospital of Guangxi Zhuangzu Autonomous Region, Nanning 530021, China;People's Hospital of Guangxi Zhuangzu Autonomous Region, Nanning 530021, China |
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| Abstract: | Objective: To prepare metronidazole cream and establish quality control standard. Methods: The cream was prepared by taking metronidazole as main components. The contents of metronidazole was determined by UV spectrometry. Results:The average recovery of metronidazole was 100. 2% , RSD was 1. 7% . Conclusion:The cream can be prepare feasibly. The method of quality control is simple,rapid and accurate. |
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| Keywords: | metronidazole cream quality control |
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