Subsequent Cancer Risk of Women Receiving Hysterosalpingography: A Nationwide Population-Based Retrospective Cohort Study |
| |
| Authors: | Yen-Hsiu Liao Cheng-Li Lin Po-Pang Tsai Wu-Chung Shen Fung-Chang Sung |
| |
| Affiliation: | 1. Department of Radiology, China Medical University Hospital, Taichung, Taiwan;2. School of Medicine, College of Medicine, China Medical University, Taichung, Taiwan;3. Management Office for Health Data, China Medical University Hospital, Taichung, Taiwan;4. Department of Biomedical Imaging and Radiological Science, College of Health Care, China Medical University, Taichung, Taiwan;5. Graduate Institute of Clinical Medical Science, School of Medicine, College of Medicine, China Medical University, Taichung, Taiwan |
| |
| Abstract: | The objective of this study was to estimate the subsequent cancer risk of women after receiving hysterosalpingography (HSG) by conducting a nationwide retrospective cohort study. We identified a study cohort of 4,371 patients who had had a HSG examination and a comparison cohort of 17,484 women without HSG examination between 1998 and 2005. Both cohorts were followed up with until the end of 2010 to measure the incidence of cancer. The risk of developing cancer for patients with HSG was assessed using the Cox proportional hazard model. In the multivariate analyses, the HSG cohort did not have a significantly greater risk of cancer (Hazard Ratio [HR] = 1.02, 95% CI = 0.79–1.31) than the non-HSG cohort. The HR was highest for genital cancer (HR = 1.32, 95% CI = 0.77–2.25), followed by urinary system cancer (HR = 1.11, 95% CI = 0.23–5.40), and abdominal cancer not involving the GU system (HR = 1.04, 95% CI = 0.53–2.03), all of which were non-significant elevations. The cancer incidence rates, especially that for urinary system cancer, were increased in the HSG cohort, but the increase in cancer incidence was small and not statistically significant. |
| |
| Keywords: | cancer cohort study hysterosalpingography National Health Insurance radiation |
|
|
