Single-cell RNA sequencing of psoriatic skin identifies pathogenic Tc17 cell subsets and reveals distinctions between CD8+ T cells in autoimmunity and cancer期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

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Single-cell RNA sequencing of psoriatic skin identifies pathogenic Tc17 cell subsets and reveals distinctions between CD8+ T cells in autoimmunity and cancer

Authors:	Jared Liu Hsin-Wen Chang Zhi-Ming Huang Mio Nakamura Sahil Sekhon Richard Ahn Priscila Munoz-Sandoval Shrishti Bhattarai Kristen M Beck Isabelle M Sanchez Eric Yang Mariela Pauli Sarah T Arron Wai-Ping Fung-Leung Ernesto Munoz Xuejun Liu Tina Bhutani Jeffrey North Wilson Liao

Institution:	1. Department of Dermatology, University of California San Francisco, San Francisco, Calif;2. Department of Dermatology, University of Michigan, Ann Arbor, Mich;3. Department of Dermatology, Howard University, Washington, DC;4. Department of Microbiology, Immunology, and Molecular Genetics, University of California Los Angeles, Los Angeles, Calif;5. Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, Tex;6. Department of Dermatology, University of Illinois at Chicago, Chicago, Ill;7. Janssen Research & Development, LLC, La Jolla, Calif

Abstract:

Keywords:	Single-cell RNA sequencing Smart-seq2 psoriasis T-cell exhaustion melanoma ELS"} {"#name":"keyword" "$":{"id":"kwrd0045"} "$$":[{"#name":"text" "_":"Ectopic lymphoid structure ERCC"} {"#name":"keyword" "$":{"id":"kwrd0055"} "$$":[{"#name":"text" "_":"External RNA Controls Consortium MAIT"} {"#name":"keyword" "$":{"id":"kwrd0065"} "$$":[{"#name":"text" "_":"Mucosa-associated invariant T PASI"} {"#name":"keyword" "$":{"id":"kwrd0075"} "$$":[{"#name":"text" "_":"Psoriasis Area and Severity Index QC"} {"#name":"keyword" "$":{"id":"kwrd0085"} "$$":[{"#name":"text" "_":"Quality control RNA-seq"} {"#name":"keyword" "$":{"id":"kwrd0095"} "$$":[{"#name":"text" "_":"RNA sequencing TCR"} {"#name":"keyword" "$":{"id":"kwrd0105"} "$$":[{"#name":"text" "_":"T-cell receptor TIL"} {"#name":"keyword" "$":{"id":"kwrd0115"} "$$":[{"#name":"text" "_":"Tumor-infiltrating lymphocyte UMAP"} {"#name":"keyword" "$":{"id":"kwrd0125"} "$$":[{"#name":"text" "_":"Uniform manifold approximation and projection
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