Downregulation of MCM2 contributes to the reduced growth potential of epithelial progenitor cells in chronic nasal inflammation |
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| Authors: | Li Yue Li Yu Tao Zhou Lin Sun Xin Yi Liu Jian Li Yue Hong Xiao Yan Ye Qing Bao Qing Xiang Meng Wei Ping Wen He Xin Chen Chun Wei Li |
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| Affiliation: | 1. Department of Otolaryngology, Guangzhou Key Laboratory of Otorhinolaryngology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China;2. Center for Stem Cell Biology and Tissue Engineering, Key Laboratory for Stem Cells and Tissue Engineering, Ministry of Education, Sun Yat-Sen University, Guangzhou, China;3. School of Medicine, Shanghai Jiao Tong University, Shanghai, China;4. Department of Otorhinolaryngology Head and Neck Surgery, Guangzhou First People’s Hospital, Guangzhou, China |
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| Abstract: | |
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| Keywords: | Human nasal epithelial progenitor cells inflamed nasal mucosa cell cycle regulation minichromosome maintenance proteins 2 (MCM2) cell growth DEG" },{" #name" :" keyword" ," $" :{" id" :" kwrd0040" }," $$" :[{" #name" :" text" ," _" :" Differentially expressed gene GO" },{" #name" :" keyword" ," $" :{" id" :" kwrd0050" }," $$" :[{" #name" :" text" ," _" :" Gene ontology hNEPC" },{" #name" :" keyword" ," $" :{" id" :" kwrd0060" }," $$" :[{" #name" :" text" ," _" :" Human nasal epithelial progenitor cell MCM" },{" #name" :" keyword" ," $" :{" id" :" kwrd0070" }," $$" :[{" #name" :" text" ," _" :" Minichromosome maintenance protein NP" },{" #name" :" keyword" ," $" :{" id" :" kwrd0080" }," $$" :[{" #name" :" text" ," _" :" Nasal polyp P" },{" #name" :" keyword" ," $" :{" id" :" kwrd0090" }," $$" :[{" #name" :" text" ," _" :" Passage RNA-seq" },{" #name" :" keyword" ," $" :{" id" :" kwrd0100" }," $$" :[{" #name" :" text" ," _" :" RNA sequencing |
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