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Characterization of the cytokine storm reflects hyperinflammatory endothelial dysfunction in COVID-19
Authors:Jonathan T. Sims  Venkatesh Krishnan  Ching-Yun Chang  Sarah M. Engle  Giacomo Casalini  George H. Rodgers  Nicoletta Bivi  Brian J. Nickoloff  Robert J. Konrad  Stephanie de Bono  Richard E. Higgs  Robert J. Benschop  Silvia Ottaviani  Anabela Cardoso  Ajay Nirula  Mario Corbellino  Justin Stebbing
Affiliation:1. Eli Lilly and Company, Indianapolis, Ind;2. Luigi Sacco Department of Clinical and Biomedical Sciences, University of Milan, Milan, Italy;3. Department of Surgery and Cancer, Imperial College, London, United Kingdom;4. Division of Infectious Diseases, ASST Fatebenefratelli Sacco, Milan, Italy
Abstract:
Keywords:COVID-19  biomarkers  cardiovascular  inflammation  Ordinal Scale  baricitinib  COVID-19"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0045"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Coronavirus disease 2019  GDF-2"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0055"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Growth/differentiation factor 2  HC"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0065"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Healthy control  MCP"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0075"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Monocyte chemoattractant protein  PARP-1"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0085"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Poly(ADP-ribose) polymerase 1  PTX3"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0095"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Pentraxin-related protein 3  SARS-CoV-2"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0105"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Severe acute respiratory syndrome coronavirus 2
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