Icotinib,an effective treatment option for patients with lung adenocarcinoma harboring compound EGFR L858R and A871G mutation |
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Authors: | Jin Lin-ling Wu Zhen-zhen Wang Yan-li Chen Dong-sheng Li Si Xiao Mingzhe Zhao Xin |
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Institution: | 1.Department of Respiratory and Critical Care Medicine, Jiangsu Province Hospital and The First Affiliated Hospital with Nanjing Medical University , Nanjing, 210002, China ;2.The State Key Laboratory of Translational Medicine and Innovative Drug Development, Jiangsu Simcere Diagnostics Co., Ltd, Nanjing, 210002, China ; |
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Abstract: | Investigational New Drugs - Compound epidermal growth factor receptor (EGFR) mutations are defined as double or multiple independent mutations of the EGFR tyrosine kinase domain (TKD), in which an... |
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