维生素D和肥胖

大量研究表明维生素D及维牛素D受体(VDR)与肥胖密切相关.血清25(OH)D及1,25(OH),D的浓度都与体重指数(BMI)呈负相关.潜在的原因可能是由于肥胖者活动少及着装习惯导致的日光照射少以及大量的维生素D储存于脂肪组织中所致.研究发现,补充维生素D有利于减轻体重.因此,肥胖者比非肥胖者更需要补充维生素D.只有增加安全、合适的日照时间,食用强化维生素D的食品或者补充高剂量的维牛素D才能保证体内充足的维生素D水平.

Vitamin D and obesity

Accumulating evidence suggests that vitamin D and vitamin D receptor( VDR) are related to obesity. Serum 25(OH)D and 1,25(OH)2D levels are inversely associated with body mass index(BMI). Underlying causes that have been suggested are less sun exposure in obese subjects due to limited mobility or clothing habits and a higher storage of vitamin D in adipose tissue. Restoration of vitamin D helps to lose weight. Thus, more vitamin D are needed in obese subjects than non-obese subjects. Correction of low 25 (OH) D concentrations can happen only if some or all of the following are implemented: the encouragement of safe, moderate exposure of skin to ultraviolet light, appropriate increase in food fortification with vitamin D,and the provision of higher doses of vitamin D in supplements for adults.