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| α-硫辛酸在糖尿病治疗中的临床应用价值 | |
| 引用本文： | 王俐,蔡美琴. α-硫辛酸在糖尿病治疗中的临床应用价值[J]. 中华临床营养杂志, 2010, 18(5): 323-326. DOI: 10.3760/cma.j.issn.1674-635X.2010.05.016 |
| 作者姓名： | 王俐 蔡美琴 |
| 作者单位： | 上海交通大学医学院营养系,200025 |
| 摘 要： | 氧化应激是糖尿病发病的重要机制，α-硫辛酸作为一种强抗氧化剂，能清除自由基，减轻氧化损伤，目前已广泛应用于糖尿病并发症的临床治疗。本文主要综述α-硫辛酸在减轻糖尿病患者的氧化应激损伤、保护糖尿病患者的血管病变、治疗糖尿病的多发性神经症状、调节胰岛素敏感性等方面的作用。 |
| 关 键 词： | α-硫辛酸 氧化应激 糖尿病 并发症 临床应用 |
Clinical value of alpha-lipoic acid in the management of diabetes mellitus |
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| WANG Li. Clinical value of alpha-lipoic acid in the management of diabetes mellitus[J]. Chinese Journal of Clinical Nutrition, 2010, 18(5): 323-326. DOI: 10.3760/cma.j.issn.1674-635X.2010.05.016 | |
| Authors: | WANG Li |
| Affiliation: | . (Department of Nutrition, Medical College, Shanghai Jiaotong University, Shanghai 200025, China) |
| Abstract: | Oxidative stress plays an important role in the progression of diabetes mellitus. As a potent antioxidant, alpha-lipoic acid is able to clear free radicals and alleviate oxidative damages and therefore has been widely applied in the clinical management of diabetes mellitus. This article summarizes the clinical application of alpha-lipoic acid in alleviating diabetes mellitus-related oxidative damages, protecting vascular lesions, treating diabetic polyneuropathies, and modulating insulin sensitivity. |
| Keywords: | Alpha-lipoic acid Oxidative stress Diabetes mellitus Complication Clinical application |
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