脉搏波速度在心血管病中的临床应用

目的：观察心血管病患者臂踝脉搏波速度（baPWV）与心血管事件和心血管危险因素的相关性。方法：连续收集296例心血管病高危患者，进行病史采集，baPWV、身高、体重、腰围、血压、心率测量及血生化检查。比较高baPWV组（≥1700cm／s，138例）与低baPWV组（〈1700cm／s，158例）患者具有危险因素的个数和临床心血管事件发生情况。结果：与低baPWV组相比，高baPWV组心血管事件发生率较高（46．8％：73．9％，P〈0．01），心血管危险因素数目较多（3．8±1．0）；（4．7±1．1），P〈0．001]。影响baPWV的因素主要为年龄（OR=4．985，P〈0．001）、收缩压（OR=4．012，P〈0．01）和脉压（OR=2．691，P〈0．05）。结论：在心血管病患者中，baPWV较高的患者心血管事件发生率高，心血管危险因素多。年龄、收缩压和脉压是影响baPWV的独立危险因素。

Application of pulse wave velocity in patients with high cardiovascular risk

Objective： To observe the relationship between brachial-ankle pulse wave velocity （baPWV） and cardiovascular risk factors as well as clinical cardiovascular events in cardiovascular patients with high risk. Methods： Relevant clinical data, including baPWV, height, weight, waist circumference, blood pressure, heart rate, history and blood biochemistry test were collected in 296 consecutive cardiovascular patients with high risk. The number of risk factors and cardiovascular events between patients with high baPWV （≥1700 cm/s, 138 cases） and low baPWV （〈 1700 cm/s, 158 cases） were compared. Results： Compared with low baPWV group, the cardiovascular events and the number of cardiovascular risk factors were higher in high baPWV group 46.8% vs. 73.9%, P〈0. 01 and （3.8 ±1.0） vs. （4.7 ±1.1）, P〈0. 005, respectively]. The factors influencing baPWV were age （OR= 4. 985, P〈 0. 001）, systolic blood pressure （OR=4. 012, P〈0. 01） and pulse pressure （OR=2. 691, P〈0. 05）. Conclusion： In cardiovascular patients with high risk, the cardiovascular events and the number of risk factors were more. Age, systolic blood pressure and pulse pressure are independent risk factors of baPWV.