无创通气在急性呼吸窘迫综合征早期中的应用

目的评价早期应用无创通气治疗急性呼吸窘迫综合征（ARDS）的价值。方法纳入25例ARDS患者，随机分成无创通气组（13例）及对照组（12例1。对照组给予气管插管呼吸机辅助通气治疗；无创通气组早期给予无创通气治疗，如患者不能耐受无创通气则序贯给予气管插管呼吸机辅助通气治疗（13例均行气管插管）。结果无创组和对照组平均气管插管天数分别为（6．50±1．00）d、（8．00±0．85）d，P〈0．05。重症医学科病房（intensiveca,reunit，ICU）住院天数，对照组（12．4±1．5）d，无创组：（11．6±1．0）d，P〈0．01，存在显著差异。ICU病死人数：对照组和无创组分别为2、3例，P=0．541，无统计学差异。结论ARDS早期应用无创通气治疗可能减少气管插管时间和ICU住院时间。

The application of noninvasive ventilation in early ARDS

Objective To investigate early use of noninvasive ventilation in acute respiratory distress syndrome（ARDS）. Meth- otis Twenty five ARDS patients were randomly assigned to noninvasive ventilation （NIV） group and the control group. Patients in the the control group were given endotracheal intubation and invasive ventialtion;the patients in noninvasive ventilation group treated with noninvasive ventilation early. If patients of the NIV group can＇t tolerate NIV,invasive ventilation was applied as soon as possible. Results The mean tracheal intubation time in the NIV group and control group were （6.50±1.00） days, （8.00±0.85）days （P〈0.05）,respectively. ICU length of stay were（ 12.4±1.5）days for the control group ,compared with（ 11.6±1.0）days（P〈0.01）for the NIV group. There was no significant difference in ICU mortality（the control group was 2/12 and NIV group were3/13,P=0.541）. Conclusion Early application of ARDS with NIV may decrease the endotracheal intubation time and ICU length of stay.