Betaine inhibits Toll-like receptor 4 expression in rats with ethanol-induced liver injury |
| |
| Authors: | Qing-Zhao Shi Lu-Wen Wang Wei Zhang Zuo-Jiong Gong |
| |
| Affiliation: | Qing-Zhao Shi, Lu-Wen Wang, Wei Zhang, Zuo-Jiong Gong, Department of Infectious Diseases, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, China |
| |
| Abstract: | ![]()
AIM:To test whether ethanol feeding could induce Toll-like receptor 4(TLR4)responses,assess the hepatoprotective effect of betaine and its inhibitive effect on TLR4 in animal models of alcoholic liver injury.METHODS:Forty-eight female Sprague-Dawley rats were randomly divided into four groups as control,model,low and high dose betaine groups.Except control group,all rats were fed with high fat-containing diet plus ethanol and fish oil gavages for 8 wk.Betaine was administered intragastrically after exposure... |
| |
| Keywords: | Betaine Toll-like receptor 4 Alcoholic liver injury Expression |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
| 点击此处可从《World journal of gastroenterology : WJG》浏览原始摘要信息 |
|
