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Recommendations for the use of common outcome measures in traumatic brain injury research |
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| Authors: | Wilde Elisabeth A Whiteneck Gale G Bogner Jennifer Bushnik Tamara Cifu David X Dikmen Sureyya French Louis Giacino Joseph T Hart Tessa Malec James F Millis Scott R Novack Thomas A Sherer Mark Tulsky David S Vanderploeg Rodney D von Steinbuechel Nicole |
| Affiliation: | a Department of Physical Medicine and Rehabilitation, Baylor College of Medicine, Houston, TX b Department of Neurology, Baylor College of Medicine, Houston, TX c Department of Radiology, Baylor College of Medicine, Houston, TX d TIRR Memorial Hermann, Houston, TX e Michael E. DeBakey Veterans' Administration Medical Center, Houston, TX f University of Texas Medical School at Houston, Houston, TX g Craig Hospital, Englewood, CO h Department of Physical Medicine and Rehabilitation, Ohio State University, Columbus, OH i Department of Rehabilitation Medicine, Rusk Institute for Rehabilitation, New York, NY j Department of Physical Medicine and Rehabilitation, Virginia Commonwealth University, PM&R Service, Hunter Holmes McGuire Veterans Administration Medical Center, Richmond, VA k Department of Rehabilitation Medicine, University of Washington, Seattle, WA l Department of Orthopaedics and Rehabilitation, Walter Reed Army Medical Center, Washington DC m JFK Johnson Rehabilitation Institute, Edison, NJ n Spaulding Rehabilitation Hospital/Harvard Medical School, Boston, MA o Moss Rehabilitation Research Institute, Elkins Park, PA p Department of Physical Medicine and Rehabilitation, Indiana University School of Medicine, Indianapolis, IN q Rehabilitation Hospital of Indiana, Indianapolis, IN r Departments of Physical Medicine and Rehabilitation and Emergency Medicine, Wayne State University School of Medicine, Detroit, MI s Department of Physical Medicine and Rehabilitation, University of Alabama at Birmingham, AL t Department of Physical Medicine and Rehabilitation, University of Michigan, Ann Arbor, MI u Psychology Service, James A. Haley Veterans' Hospital, Tampa, FL v Departments of Psychology and Psychiatry, University of South Florida, Tampa, FL w Department of Medical Psychology and Medical Sociology, University Medical Center Göttingen Georg-August-University, Göttingen, Germany |
| Abstract: | Wilde EA, Whiteneck GG, Bogner J, Bushnik T, Cifu DX, Dikmen S, French L, Giacino JT, Hart T, Malec JF, Millis SR, Novack TA, Sherer M, Tulsky DS, Vanderploeg RD, von Steinbuechel N. Recommendations for the use of common outcome measures in traumatic brain injury research.This article summarizes the selection of outcome measures by the interagency Traumatic Brain Injury (TBI) Outcomes Workgroup to address primary clinical research objectives, including documentation of the natural course of recovery from TBI, prediction of later outcome, measurement of treatment effects, and comparison of outcomes across studies. Consistent with other Common Data Elements Workgroups, the TBI Outcomes Workgroup adopted the standard 3-tier system in its selection of measures. In the first tier, core measures included valid, robust, and widely applicable outcome measures with proven utility in TBI from each identified domain, including global level of function, neuropsychological impairment, psychological status, TBI-related symptoms, executive functions, cognitive and physical activity limitations, social role participation, and perceived health-related quality of life. In the second tier, supplemental measures were recommended for consideration in TBI research focusing on specific topics or populations. In the third tier, emerging measures included important instruments currently under development, in the process of validation, or nearing the point of published findings that have significant potential to be superior to some older (“legacy”) measures in the core and supplemental lists and may eventually replace them as evidence for their utility emerges. |
| Keywords: | Outcome assessment health care Brain injuries Neurobehavioral manifestations Research Rehabilitation |
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