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| 海洛因依赖者脱毒后外周血大颗粒淋巴细胞的变化——附54例观察分析 | |
| 引用本文： | 黄莉,吴乐平,杨正安,何国庆,王湘黔,夏曙华,王伟.海洛因依赖者脱毒后外周血大颗粒淋巴细胞的变化——附54例观察分析[J].中国药物依赖性杂志,2001,10(2):116-118. |
| 作者姓名： | 黄莉 吴乐平 杨正安 何国庆 王湘黔 夏曙华 王伟 |
| 作者单位： | 1. 贵阳医学院附属医院临检科, 2. 贵州省安宁医院, 3. 贵州省人民医院, 4. 贵阳市南明公安分局戒毒所, |
| 摘 要： | 目的··:研究海洛因依赖者脱毒前后外周血大颗粒淋巴细胞的变化。方法··:采用瑞氏 -姬姆萨染色法 ,检测54例海洛因依赖者脱毒前后外周血中大颗粒淋巴细胞所占的百分率。结果··:海洛因依赖者脱毒前总大颗粒淋巴细胞低于对照组 ,有非常显著性差异 (P<0.01) ;女性略高于男性无显著性差异 (P>0.05) ;脱毒后总大颗粒淋巴细胞高于对照组 ,有非常显著性差异 (P<0.01) ;女性明显高于男性 ,有非常显著性差异 (P<0.01)。结论··:海洛因依赖者脱毒后外周血大颗粒淋巴细胞显著增高 ,这可作为初步评价海洛因依赖者脱毒后自然免疫力状态的一项指标。 |
| 关 键 词： | 海洛因依赖 大颗粒淋巴细胞 免疫功能 |
| 修稿时间： | 2000年3月20日 |
LARGE GRANULAR LYMPHOCYTES OF PERIPHERY BLOOD IN HEROIN ADDICTS |
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| HUANG Li,WU Leping,YANG Zheng'an,HE Guoqing,WANG Xiangqian,XIA Shuhua,WANG Wei.LARGE GRANULAR LYMPHOCYTES OF PERIPHERY BLOOD IN HEROIN ADDICTS[J].Chinese Journal of Drug Dependence,2001,10(2):116-118. | |
| Authors: | HUANG Li WU Leping YANG Zheng'an HE Guoqing WANG Xiangqian XIA Shuhua WANG Wei |
| Institution: | HUANG Li1,WU Leping2,YANG Zheng'an1,HE Guoqing3,WANG Xiangqian4,XIA Shuhua1,WANG Wei1 1 |
| Abstract: | Objective: To study the change of the large granular lymphocytes(LGL)of periphery blood in heroin addicts. Method: The percentage of LGL in 54 patients before and after detoxification was detected by Wright and Gimsa stain. Result: The number of total LGL before detoxification was lower than that of control(P<0.01); and women 's LGL level was little higher than men's(P>0.05); the number of total LGL after detoxification was higher than that of control (P<0.01); and women's LGL level was much higher than men's (P<0.01).Conclusion: There is great change in the LGL level of drug addicts after detoxification, which could be an index to estimate preliminarily immune state in heroin addicts. |
| Keywords: | heroin dependence large granular lymphocyte immunofunction |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |