| 低剂量染石英尘大鼠支气管肺泡冲洗液磷脂谱变化的研究 |
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| 引用本文： | 田琳,郭鼐.低剂量染石英尘大鼠支气管肺泡冲洗液磷脂谱变化的研究[J].工业卫生与职业病,1991,17(1):1-4. |
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| 作者姓名： | 田琳 郭鼐 |
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| 作者单位： | 山西医学院卫生系，山西医学院卫生系，山西医学院卫生系，山西医学院卫生系，山西医学院卫生系 太原市新建南路10号 030001，太原市新建南路10号 030001，太原市新建南路10号 030001，太原市新建南路10号 030001，太原市新建南路10号 030001 |
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| 摘 要： | 本文报道了给大鼠气管注入低剂量石英尘后其BALF中总磷脂、DPPC、PI、PS、Sph和LPC含量的动态变化。实验分为对照组和石英组,分别于染尘后7天、15天、60天和120天分组剖检。结果表明,总磷脂、DPPC染尘后7～120天一直呈上升趋势,Sph、PI也明显增加,PS、LPC无明显改变。并对结果进行了讨论。
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| 关 键 词： | 石英 支气管肺泡 冲洗液 磷脂 |
STUDY OF PHOSPHOLIPID SPECTRUM IN RAT BRONCHOALVEOLAR LAVAGE FLUID AFTER INSTILLING LOW DOSE OF QUARTZ DUST |
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| Tian Lin et al.STUDY OF PHOSPHOLIPID SPECTRUM IN RAT BRONCHOALVEOLAR LAVAGE FLUID AFTER INSTILLING LOW DOSE OF QUARTZ DUST[J].Industrial Health and Occupational Diseases,1991,17(1):1-4. |
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| Authors: | Tian Lin |
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| Abstract: | Changes of the contents of total phospholipid, DPPC, PI, PS, Sph, and LPC in rats' bronchoalveolar lavage fluid (BALF) after instilling intra-tracheally low doses of quartz were observed.The rats were divided into 2 groups: control and quartz ones. All rats were killed at intervals of 7, 15, 60 and 120 days after instillation. The results indicated that there was an increasing tendency of the contents of total phospholipid and DPPC during 7-120 days after instillation. The contents of PI and Sph were significantly higher than those of the control group. No significant increase in contents of PS and LPC was observed. The results were discussed. |
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| Keywords: | quartzj bronchoalveolar lavage phospholipid |
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