食管癌伴糖尿病患者调强放疗后放射性肺炎发生的临床研究

目的 分析伴有糖尿病的食管癌患者接受调强放射治疗后放射性肺炎的发生情况。方法 回顾性分析徐州市肿瘤医院2015年6月-2017年6月收治的50例糖尿病食管癌患者作为实验组，同时选取该院收治50例非糖尿病食管癌患者作为对照组，两组食管癌患者均接受调强放射治疗，对比两组放射治疗食管癌患者放射性肺炎的发生率。结果 实验组糖尿病食管癌患者经调强放射治疗后，放射性肺炎发生率为34%，对照组非糖尿病食管癌患者经治疗后，放射性肺炎发生率为14%，两组食管癌患者给予调强放射治疗后放射性肺炎的发生率有显著性差异（P<0.05）。结论 食管癌合并糖尿病的患者经调强放射治疗后，较易出现放射性肺炎的情况。

Clinical study of radiation pneumonitis in patients with esophageal cancer and diabetes after intensity-modulated radiotherapy

Objective To analyze the accidence of radiation pneumonitis in patients with esophageal cancer with diabetes mellitus after intensity-modulated radiotherapy.Methods A retrospective analysis was performed in xuzhou tumor hospital from June 2015 to June 2017. 50 cases of diabetic patients with esophageal cancer as experimental group and 50 patients with non-diabetic esophageal cancer were selected as control group. The incidence of radiation pneumonia in patients with esophageal cancer was compared between the two groups.Result In the experimental group, the incidence of radiation pneumonitis was 34% in patients with esophageal cancer after IMRT. In the control group, the incidence of radiation pneumonitis was 14% after treatment. There were significant differences in incidence of radiation pneumonitis between two groups of esophageal cancer patients(P<0.05).Conclusion The incidence of radiation pneumonitis is more common in patients with esophageal cancer with diabetes after intensity modulated radiation therapy.