| 蒽环类药物相关心脏毒性的研究进展 |
| |
| 引用本文： | 郭辅定,赖燕秋.蒽环类药物相关心脏毒性的研究进展[J].疑难病杂志,2021(3). |
| |
| 作者姓名： | 郭辅定 赖燕秋 |
| |
| 作者单位： | 武汉大学人民医院心内科/武汉大学心脏自主神经研究中心/武汉大学心血管病研究所/心血管病湖北省重点实验室 |
| |
| 基金项目： | 国家自然科学基金资助项目(81770364、81530011)。 |
| |
| 摘 要： | 蒽环类药物是治疗恶性肿瘤最有效的化疗药物之一,临床广泛用于治疗血液系统恶性肿瘤和实体肿瘤。心脏毒性是蒽环类药物潜在的严重不良反应,也是限制其临床应用的重要考量因素。目前,蒽环类药物相关心脏毒性尚缺乏有效的治疗手段,早期监测和提前预防蒽环类药物相关心脏毒性的发生尤为重要。文章就蒽环类药物相关心血管疾病的发生机制、监测手段及防治策略进行综述,以期为临床防治蒽环类药物相关心脏毒性提供新思路。
|
| 关 键 词： | 蒽环类药物 心脏毒性 发病机制 不良反应 |
Research progress of anthracycline-related cardiotoxicity |
| |
| Institution: | (Department of Cardiology, Renmin Hospital of Wuhan University,Hubei Province,Wuhan 430060,China) |
| |
| Abstract: | Anthracyclines are one of the most effective chemotherapeutics for the treatment of malignant tumors,and are widely used clinically to treat hematological malignancies and solid tumors.Cardiotoxicity is a potentially serious adverse reaction of anthracyclines,and it is also an important factor limiting its clinical application.At present,there is no effective treatment for anthracycline-related cardiotoxicity.Early monitoring and prevention of anthracycline-related cardiotoxicity are particularly important.This article reviews the occurrence mechanism,monitoring methods and prevention and treatment strategies of anthracycline-related cardiovascular diseases,in order to provide new ideas for the clinical prevention and treatment of anthracycline-related cardiotoxicity. |
| |
| Keywords: | Anthracyclines Cardiotoxicity Pathogenesis Adverse reaction |
| 本文献已被 维普 等数据库收录！ |
|
