| 河北甜杏仁对D-半乳糖诱导衰老模型大鼠的影响 |
| |
| 引用本文： | 王晖,张淑华,郭爱民,张锦楠.河北甜杏仁对D-半乳糖诱导衰老模型大鼠的影响[J].卫生研究,2004,33(2):222-224. |
| |
| 作者姓名： | 王晖 张淑华 郭爱民 张锦楠 |
| |
| 作者单位： | 1. 首都医科大学卫生化学教研室,北京,100054
2. 首都医科大学化学教研室 |
| |
| 摘 要： | 目的 研究河北甜杏仁对D 半乳糖 (D gal)诱导衰老模型大鼠的影响。方法 给D 半乳糖衰老模型大鼠饲以不同杏仁剂量 ( 32 5、6 5、97 5g kg饲料 )的饲料 ,30天后 ,测定大鼠血清中丙二醛 (MDA)水平、超氧化物歧化酶 (SOD)、谷胱甘肽过氧化物酶 (GSH Px)的活力以及红细胞膜脂质流动性。结果 与衰老组比较 ,高、中剂量组大鼠血清中MDA明显降低 (P <0 0 1) ,SOD、GSH Px活力明显提高 (P <0 0 1) ,红细胞膜脂质流动性明显增强 (P <0 0 1)。而低剂量组各项指标均没有明显变化 (P >0 0 5 )。结论 甜杏仁具有一定的抗氧化、延缓衰老的作用
|
| 关 键 词： | 甜杏仁 D-半乳糖 x 红细胞膜 |
| 文章编号： | 1000-8020(2004)02-0222-03 |
| 修稿时间： | 2003年8月14日 |
Effects of almond on D-gal-induced aging rats |
| |
| Hui Wang,Shuhua Zhang,Aimin Guo,Jinnan Zhang.Effects of almond on D-gal-induced aging rats[J].Journal of Hygiene Research,2004,33(2):222-224. |
| |
| Authors: | Hui Wang Shuhua Zhang Aimin Guo Jinnan Zhang |
| |
| Institution: | Department of Sanitary Chemistry, Capital University of Medicine Science, Beijing 100054, China. |
| |
| Abstract: | Objective To study the effects of Beijing Almond on D gal induced aging rats. Methods D gal induced aging rats are fed on almond in three different dosages respectively daily (32 5g/kg feedstuff, 65g/kg feedstuff, 97 5g/kg feedstuff). After 30 days, the level of MDA, the activities of SOD, GSH Px in serum, and the liquid fluidity of erythrocyte membrane were determined. Results Compared with aging group, the level of MDA in high and middle dose groups decreased significantly ( P <0 01). At the same time, the activities of SOD, GSH Px and the liquid fluidity of erythrocyte membrane increased evidently ( P <0 01). But the lowest dose group was not significantly difference ( P >0 05). Conclusion Almond in proper has abilities of anti oxidation and retarding aging process. |
| |
| Keywords: | almond D gal MDA SOD GSH Px erythrocyte membrane |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
