Synthesis and anthelmintic activity of carbamates derived from imidazo[2,1-b][1,3,4]thiadiazole and imidazo[2,1-b]thiazole. |
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Authors: | A Marin N Valls F J Berenguer M T Alonso A Ramon Martinez M Mercedes Martinez J Elguero |
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Affiliation: | Departamento de Quimica Organica, Facultad de Farmacia, Universidad de Barcelona, Spain. |
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Abstract: | The anthelmintic activity of 25 compounds, most of them carbamates, was determined. The in vitro results are interesting and show that an aromatic azapentalene can replace the benzimidazole ring without loss of its biological properties. The in vivo results, however, show that the compounds are devoid of practical interest. |
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