特发性肺间质纤维化与其它肺间质性病变的HRCT表现

目的:提高对慢性肺间质性疾病的认识。方法:回顾性分析18例特发性肺间质纤维化(IPF)及20例继发慢性肺间质性疾病的临床及高分辨率CT(HRCT)表现特点。结果:慢性肺间质性疾病的主要HRCT表现为异常线样影、蜂窝影、磨玻璃影及结节影。IPF的HRCT的特征主要表现为网状影或蜂窝影,病变主要分布于两肺基底部、肺外带胸膜下。在临床上有典型的进行性呼吸困难,常伴杵状指、发绀及肺底部的爆裂音。结论:IPF在临床及HRCT表现上有其特点,有别于继发性肺间质性病变。

The HRCT appearances of idiopathic pulmonary fibrosis and other interstitial lung disease

Objective: To increase the cognition to the interstitial lung disease.Methods: Eighteen cases of idiopathic pulmonary fibrosis(IPF) and twenty cases of interstitial lung disease with other causes were retrospectively analyzed by clinical feature and high resolution computed tomography(HRCT) characteristics.Results: Interstitial lung disease had the following HRCT findings: abnormal lines,honeycombing,ground-glass opacity and nodules.In IPF patients,the reticular or honeycombing were found in HRCT and mostly distribute along the bottom of lung and subpleural.The main clinical manifestations were typical proceeding dyspnea,clubbing fingers,cyanopathy and velcro rales.Conclusion: The IPF has characteristics on clinic and HRCT,and is different from interstitial lung disease with other causes.