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小蓟的化学成分研究
引用本文:冯子明,杨桠楠,姜建双,张培成.小蓟的化学成分研究[J].中国实验方剂学杂志,2012,18(6):87-89.
作者姓名:冯子明  杨桠楠  姜建双  张培成
作者单位:天然药物活性物质与功能国家重点实验室,中国医学科学院北京协和医学院药物研究所,北京 100050
基金项目:国家科技重大专项(2011ZX09307-002-01)
摘    要:目的:研究菊科蓟属植物刺儿菜Cirsium setosum地上部分(小蓟)的化学成分.方法:通过各种柱色谱进行分离纯化,根据理化性质和波谱数据进行结构鉴定.结果:分离并鉴定了9个化合物,分别为伪蒲公英甾醇(1),伪蒲公英甾醇醋酸酯(2),谷甾醇(3),反式对香豆酸二十六醇酯(4),芹菜素(5),异山萘甲黄素(6),胡萝卜苷(7),芦丁(8),蒙花苷(9).结论:化合物2,4,6为首次从小蓟中分离得到.

关 键 词:小蓟  菊科  蓟属  化学成分
收稿时间:2011/10/28 0:00:00

Chemical Constituents from Cirsium setosum
FENG Zi-ming,YANG Ya-nan,JIANG Jian-shuang and ZHANG Pei-cheng.Chemical Constituents from Cirsium setosum[J].China Journal of Experimental Traditional Medical Formulae,2012,18(6):87-89.
Authors:FENG Zi-ming  YANG Ya-nan  JIANG Jian-shuang and ZHANG Pei-cheng
Institution:State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100050, China;State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100050, China;State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100050, China;State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100050, China
Abstract:Objective:To study the chemical constituents from the flowers of Cirsium setosum.Method:Compounds were isolated by chromatographic techniques.Their structures were elucidated by spectral methods.Result:Nine compounds were identified as pseudotaraxasterol(1),pseudotaraxasteryl acetate(2),β-sitosterol(3),(E)-hexacosyl p-coumarate(4),apigenin(5),isokaempferide(6),β-carotene(7),rutin(8),buddleoside(9).Conclusion:Compounds 2,4,6 were isolated from Cirsium setosum for the first time.
Keywords:Cirsium setosum  Asteraceae  Cirsium   chemical constituent
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