| 微量元素与前列腺癌发病危险的病例—对照研究 |
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| 引用本文： | 安宁 何维敬. 微量元素与前列腺癌发病危险的病例—对照研究[J]. 微量元素与健康研究, 2000, 17(4): 17-19 |
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| 作者姓名： | 安宁 何维敬 |
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| 作者单位： | 济南市卫生防疫站,济南 |
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| 基金项目： | 山东省自然科学基金资助 !( 971 2 0 4 8) |
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| 摘 要： | 目的 :为探讨血清微量元素含量与前列腺癌发病危险的关系。方法 :对 96例前列腺癌新发病例实施 1∶ 3配比的病例—对照研究。结果 :前列腺癌病例与医院非癌对照、正常对照比较 ,血清 Se(OR分别为 0 .62 ,0 .53)、Zn(OR分别为 0 .60 ,0 .58)、Cu/Zn(OR分别为 1 .70 ,1 .63)水平上差异有显著性 (P<0 .0 5) ,且与前列腺癌的发病危险存在剂量 -反应关系。结论 :提示血清 Se、Zn的降低及 Cu/Zn水平的升高可能是前列腺癌发病的危险因素
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| 关 键 词： | 前列腺癌 微量元素 病例-对照研究 |
Studies on the relationship between prostatic cancer and trace elements:a case-control studies |
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| An NIng,He Weijing,Pang Weiqiu. Studies on the relationship between prostatic cancer and trace elements:a case-control studies[J]. Studies of Trace Elements and Health, 2000, 17(4): 17-19 |
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| Authors: | An NIng He Weijing Pang Weiqiu |
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| Abstract: | Objective In order to evaluate the correlation of trace elements to prostatic cancer.Methods A hospital-based case-control study was conducted in 5 hospitals of Jinan.A total of 96 cases of histologically confirmed prostatic cancer diagnosed between 1997～1999 and 288 controls of comparable age,sex,and nationality were interviewed in the study.Results Compared the prostatic cancer cases with non-cancer cases and neighborhood controls,selenivmlor (OR=0.53～0.62),Cu/Zn(OR=1.63～1.70) were significanty related to prostatic cancer and had a dose-response relationship with the risk of prostatic cancer.Conclusions It is concluded that lackness of Selenium or Zinc and with high level of Cu/Zn may increase the risk of prostatic cancer. |
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| Keywords: | Prostatic cancer Trace element Case-control study |
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