Immobilization device for in vivo and in vitro multimodality image registration of rodent tumors. |
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Authors: | Nicolas Christian John A Lee Anne Bol Marc De Bast Bernard Gallez Vincent Grégoire |
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Affiliation: | Center for Molecular Imaging and Experimental Radiotherapy, Université Catholique de Louvain, Brussels, Belgium. |
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Abstract: | Biological image-guided radiotherapy requires that PET accurately identifies biologically relevant sub-volumes within a tumor. In this framework, an immobilization device was developed to study multi-imaging (CT, micro-MRI, micro-PET, and autoradiography) registration of mouse tumors. The registration accuracy assessed by calculating the average minimal distance between two skew lines was in the order of 0.2-0.3 mm. |
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