新生儿呼吸道感染病原体的分布及耐药情况分析

目的探讨新生儿呼吸道病原体的分布及耐药情况。方法取我院新生儿172例患儿呼吸道感染的痰标本进行检测,分析其病原体分布及耐药情况。结果主要病原菌为大肠埃希菌(37株)、肺炎克雷伯菌(28株)以及金黄色葡萄球菌(13株);此外还检验出36株呼吸道合胞病毒、22株柯萨奇病毒、18株腺病毒、14株EB病毒、48株肺炎支原体、25株肺炎衣原体、其他9例。常见革兰氏阴性菌对美洛西林舒巴坦、头孢呋辛、头孢他啶、美罗培南较为敏感,金黄色葡萄球菌对红霉素与青霉素有显著的耐药性。结论合理使用抗生素,对于医疗质量水平的提高具有重要意义。

Distribution of neonatal respiratory tract infection pathogens and drug resistance

Objective To investigate the distribution of neonatal respiratory pathogens and drug resistance.Methods The sputum of 172 children with neonatal respiratory infections were collected and analyzed. Results The main pathogens were Escherichia coli（ 37 strains）,Klebsiella pneumoniae（ 28 strains） and Staphylococcus aureus（ 13 strains）. Besides,there were 36 strains of respiratory syncytial virus,22 strains of Coxsackie virus,18strains of adenovirus,14 strains of EB virus,25strains of Chlamydia pneumoniae and 9 strains of other virus. The common gram-negative bacteria showed a high sensitivity to mezlocillin sulbactam,cefuroxime,ceftazidime and meropenem,and staphylococcus aureus showed a high resistance to erythromycin and penicillin. Conclusion The rational use of antibiotics has important significance on the improvement of quality of care.