尘肺并发慢性阻塞性肺疾病的危险因素分析

目的 分析尘肺合并慢性阻塞性肺疾病患者资料,对其危险因素进行探讨。 方法 选择浙江医院2015年3月—2018年4月间收治的109例尘肺合并慢性阻塞性肺疾病的患者为观察组,105例尘肺未合并慢性阻塞性肺疾病的患者为对照组。对2组年龄、性别、接尘工龄、尘肺分期、吸烟史、BMI、COPD家族史以及居住环境等情况进行统计,并采用单因素和多因素分析确定尘肺合并慢性阻塞性肺疾病的危险因素。 结果 单因素分析结果显示2组年龄、接尘工龄、尘肺分期、吸烟史、COPD家族史以及居住环境等比较差异有统计学意义。多因素logistic回归分析结果显示:年龄(OR=3.005,P=0.016)、接尘工龄(OR=2.443,P=0.023)、尘肺分期(OR=2.699,P=0.028)、吸烟史(OR=2.419,P=0.008)、COPD家族史(OR=3.036,P=0.008)以及居住环境(OR=2.668,P=0.014)是尘肺合并慢性阻塞性肺疾病的危险因素。 结论 年龄、接尘工龄、尘肺分期、吸烟史、COPD家族史以及居住环境是尘肺合并慢性阻塞性肺疾病的危险因素,临床中要对这些危险因素加以重视,定期对患者进行体检,提高患者生活质量,预防慢性阻塞性肺疾病的发生。 

Risk factors analysis of pneumoconiosis complicated with chronic obstructive pulmonary disease

Objective To analyze the data of pneumoconiosis complicated with chronic obstructive pulmonary disease and investigate the risk factors. Methods A total of 109 patients with pneumoconiosis complicated with chronic obstructive pulmonary disease admitted to our hospital from March 2015 to April 2018 were selected as observation group. Total 105 patients with pneumoconiosis without chronic obstructive pulmonary disease were selected as the control group. The age, sex, dusting age, pneumoconiosis stage, smoking history, BMI, family history of COPD, and living environment were counted, and the risk factors of pneumoconiosis complicated with chronic obstructive pulmonary disease were determined by single factor and multivariate analysis. Results Univariate analysis showed that there are significant different between two group on age, dusting age, pneumoconiosis, smoking history, family history of COPD, and living environment. And multivariate logistic regression analysis showed that age(OR=3.005, P=0.016), dusting age(OR=2.443, P=0.023), pneumoconiosis(OR=2.699, P=0.028), smoking history(OR=2.419, P=0.008), family history of COPD(OR=3.036, P=0.008), and living environment(OR=2.668, P=0.014) were risk factors for pneumoconiosis with chronic obstructive pulmonary disease. Conclusion Age, dusting age, pneumoconiosis stage, smoking history, family history of COPD and living environment are risk factors for pneumoconiosis complicated with chronic obstructive pulmonary disease. These risk factors should be paid attention to in clinical practice, and patients should be examined regularly to improve patients. Quality of life to prevent the occurrence of chronic obstructive pulmonary disease.