放射性皮肤损伤经不同护理措施干预的效果对比

目的 探讨医用射线防护剂(奥克喷)联合磺胺嘧啶银乳霜对放射性皮肤损伤(简称:放疗皮损)的防治效果。 方法 选取2017年1月—2018年12月浙江绿城心血管病医院接诊的鼻咽癌首诊患者,采用随机数字表法,将接受直线加速器放射治疗的150例鼻咽癌患者随机分成3组,每组50例。对3组分别施行不同的护理干预措施。观察Ⅰ组:放疗前,在照射区采用医用射线防护喷剂奥克喷,外用。观察Ⅱ组:放疗前,在照射区采用医用射线防护喷剂奥克喷,外用。放疗后,在照射区采用磺胺嘧啶银乳膏,外用。对照组:采用常规护理方法。至总疗程结束,比较3组放疗皮损的发生情况(发生率、发生时间、严重程度)及创面愈合情况(愈合时间、愈合率)。 结果 3组放疗皮损的发生率均为100%。3组放疗皮损出现的时间比较,差异有统计学意义(F=3.329,P<0.05),观察Ⅱ组的放疗皮损发生更晚。3组放疗皮损的程度比较,差异有统计学意义(P<0.05),观察Ⅱ组中严重放疗皮损(Ⅲ~Ⅳ级)的发生率更低。3组放疗皮损经治疗干预后的临床疗效比较差异有统计学意义(P<0.05),观察Ⅱ组的临床效果更好。3组放疗皮损愈合时间比较,差异有统计学意义(P<0.05),观察Ⅱ组的放疗皮损愈合时间更短。3组已愈合创面百分率比较,差异有统计学意义(P<0.05),观察Ⅱ组的已愈合创面百分率更高。 结论 对鼻咽癌患者的放射性皮肤损伤,采用奥克喷联合磺胺嘧啶银,可以更好地减轻放疗皮损,促进放疗皮损创面的愈合。 

Intervention effect of different nursing measures on radiation skin injury

Objective To explore the preventive and therapeutic effects of medical radiation protector(ork) combined with sulfadiazine silver cream on radiation skin lesions. Methods From January 2017 to December 2018 in Greentown Cardiovascular Hospital, a total of 150 patients with nasopharyngeal carcinoma who received linear accelerator radiotherapy were randomly divided into three groups, 50 cases in each group. Three groups were given different nursing intervention measures. In observation group Ⅰ, the medical radiation protection spray-Oak spray was used in the irradiation area for external use before radiotherapy. In observation group Ⅱ,the medical radiation protection spray-Oak spray was used in the irradiation area for external use before radiotherapy. After radiotherapy, silver sulfadiazine cream was used for external use in the irradiation area. In control group, routine nursing method was adopted. By the end of the total course of treatment, the incidence of skin lesions(incidence, occurrence time, severity) and wound healing(healing time, healing rate) were compared among the three groups. Results The incidence of skin lesions after radiotherapy was 100% in all three groups. There was significant difference in the occurrence time of skin lesions in three groups(F=3.329, P<0.05). The occurrence of skin lesions in group Ⅱ was later. There was significant difference in the degree of skin lesions after radiotherapy among the three groups(P<0.05). The incidence of severe radiation lesions(grade Ⅲ-Ⅳ) was lower in group Ⅱ. The total effective rate of the three groups after treatment and intervention was significantly different(P<0.05), and the clinical effect of group Ⅱ was better. The healing time of skin lesions in three groups was significantly different(P<0.05). The healing time of skin lesions in group Ⅱ was shorter. There was significant difference in the percentage of healed wounds among the three groups(P<0.05). The percentage of healed wounds in group Ⅱ was higher. Conclusion Oxypent combined with silver sulfadiazine can better reduce the incidence of radiation-induced skin lesions and promote the healing of radiation-induced skin lesions in patients with nasopharyngeal carcinoma.