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阿尔兹海默病的智能诊断方法
引用本文:尹义龙,袭肖明,孟宪静. 阿尔兹海默病的智能诊断方法[J]. 山东大学学报(医学版), 2020, 58(8): 14-21. DOI: 10.6040/j.issn.1671-7554.0.2019.1503
作者姓名:尹义龙  袭肖明  孟宪静
作者单位:1. 山东大学软件学院机器学习与数据挖掘实验室,山东 济南250101
2. 山东建筑大学计算机科学与技术学院,山东 济南 250101
3. 山东财经大学计算机科学与技术学院,山东 济南 250014
基金项目:国家自然科学基金(61876098);国家自然科学基金(61701280);国家自然科学基金(61801263);国家重点研发专项计划(2018YFC0830102)
摘    要:
随着人口老龄化的日渐严重,阿尔兹海默病(AD)的相关研究已成为重要的公共卫生课题。然而,目前尚无药物能够治愈AD,早发现、早治疗有助于延缓该疾病的发展。在众多的AD辅助诊断工具中,神经影像对于AD的早期诊断具有重要作用,已成为一个热门的研究课题。对基于神经影像的AD智能诊断方法进行综述,从基于单模态影像的智能AD诊断和多模态融合的智能AD诊断两方面对现有方法进行了分析,并对未来的研究方向进行了展望,有利于为AD的诊断提供新观点和新思路。

关 键 词:阿尔兹海默病  神经影像  智能诊断  
收稿时间:2019-12-27

Intelligent diagnosis methods of Alzheimer's disease
Yilong YIN,Xiaoming XI,Xianjing MENG. Intelligent diagnosis methods of Alzheimer's disease[J]. Journal of Shandong University:Health Sciences, 2020, 58(8): 14-21. DOI: 10.6040/j.issn.1671-7554.0.2019.1503
Authors:Yilong YIN  Xiaoming XI  Xianjing MENG
Affiliation:1. MLA Lab in School of Software, Shandong University, Jinan 250101, Shandong, China
2. School of Computer Science and Technology, Shandong Jianzhu University, Jinan 250101, Shandong, China
3. School of Computer Science and Technology, Shandong University of Finance and Economics, Jinan 250014, Shandong, China
Abstract:
As the number of elderly people increases, Alzheimer's disease (AD) has become a tremendous economic and societal burden. The research on AD has been considered an important global public health topic. However, there is currently no cure for AD; therefore, early detection is very helpful for the diagnosis. Neuroimaging plays an important role for the early diagnosis of AD among all detection tools and has attracted great attention in recent years. In order to provide new insights into the intelligent diagnosis methods of AD, this paper reviews the recent advances including methods based on single-modality and multi-modality and discusses the future work.
Keywords:Alzheimer's disease  Neuroimaging  Intelligent diagnosis  
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