不同剂量咪达唑仑加舒芬太尼用于腰硬联合麻醉效果观察

目的探讨咪达唑仑加舒芬太尼用于联合麻醉时的最小有效剂量。方法随机选择100例择期下腹部手术的女性患者,分为Ⅰ、Ⅱ、Ⅲ、Ⅳ4组,分别采用0.02、0.04、0.06和0.08 mg/kg咪达唑仑辅助舒芬太尼0.1μg/kg进行腰硬联合麻醉,比较4组患者镇静和遗忘程度、生命体征及并发症。结果镇静、遗忘程度依次为Ⅳ组>Ⅲ组>Ⅱ组>Ⅰ组,但Ⅳ组舌后坠发生率最高。结论 0.04～0.06 mg/kg的咪达唑仑辅助0.1μg/kg舒芬太尼有良好的镇静遗忘作用,并可有效预防内脏牵拉反应。

Effect observation of different doses of midazolam and sufentanil on combined spinal-epidural anesthesia

Objective To explore the minimum effective dose of midazolam and sufentanil on combined spinal-epidural anesthesia.Methods A total of 100 female patients with hypogastrium operation were divided into groups Ⅰ,Ⅱ,Ⅲ and Ⅳ.The four groups received midazolam 0.02,0.04,0.06 and 0.08 mg/kg combined with sufentanil 0.1 μg/kg for spinal-epidural anesthesia respectively.The degree of sedation and amnesia,vital signs and complications in the four groups were compared.Results The degree of sedation and amnesia was as follows: groups Ⅳ>Ⅲ>Ⅱ>Ⅰ,but the incidence of glossocoma in group Ⅳ was the highest.Conclusion Midazolam 0.04-0.06 mg/kg combined with sufentanil 0.1 μg/kg has satisfying effect of sedation and amnesia and it can effectively prevent the visceral guyed reaction.