Salivary flow, saliva, pH and buffering capacity in 70-year-old men and women

A representative systematic selection of 30% of all 70-year-olds (1148 persons) in Göteborg were invited to a population study. The participation rate was 85%. Sixteen per cent of the men and 25% of the women reported dryness in the mouth (sex. diff. P<0.01). There was a significant correlation between the number of drugs consumed by the subjects and subjective dryness (in both sexes P<0.001). Intake of drugs from the groups of anticholionergics, antihistamines, sedatives, hypnotics or phenothiazines respectively seemed to have the highest predicative value for dryness in the mouth (men P<0.05 and women P<0.01). There was also a positive correlation between subjective dryness and number of definable diseases in both sexes (P<0.01). In a consecutive sample (fifty-eight men and fifty-three women) a study of salivary flow, direct pH and buffer effect were performed. The mean value of unstimulated salivary secretion was in men 0.25 and in women 0.18ml/min. Corresponding figures for stimulated secretion was 1.65 and 1.04ml/min (sex. diff. P<0.01). A significantly lower unstimulated secretion was noted in women with subjective dryness (P<0.01). A negative significant correlation were found between dental invalidity, according to Eichner's classification, and stimulated secretion when drug treatment had been considered (men P<0.05 and women P<0.01). Only weak relations were noted between salivary secretions and drug treatment. Only intake of drugs with diuretic effect were negatively correlated to stimulated secretion (P<0.01). Diseases of the circulatory system were correlated to subjective dryness (P<0.01).