Bioavailability of phenytoin. A comparison of two preparations |
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| Authors: | M. J. Stewart B. R. Ballinger E. J. Devlin A. Y. Miller A. C. Ramsay |
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| Affiliation: | (1) Dundee Psychiatric Service, Strathmartine Hospital and Royal Dundee Liff Hospital, University of Dundee, Dundee, U.K. |
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| Abstract: | ![]()
Summary Plasma phenytoin levels were measured in 60 patients under steady-state conditions for a period of six weeks. During the trial, the preparation of phenytoin was changed from Phenytoin BP (Regent) to Epanutin Infatabs. A significant increase in plasma phenytoin levels following the change of tablet was matched by a decrease in the number of seizures. |
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| Keywords: | Anticonvulsants phenytoin diphenylhydantoin bioavailability |
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