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Bronchiolitis obliterans organizing pneumonia (BOOP) after thoracic radiotherapy for breast carcinoma |
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| Authors: | Robin Cornelissen Suresh Senan Imogeen E Antonisse Hauw Liem Youke KY Tan Arjan Rudolphus Joachim GJV Aerts |
| Affiliation: | 1. Dept of Pulmonary Diseases, Sint Franciscus Gasthuis, Rotterdam, The Netherlands 2. Dept of Pulmonary Diseases, Erasmus Medical Center, Rotterdam, The Netherlands 3. Dept of Radiation Oncology, VU University Medical Center, Amsterdam, The Netherlands 4. Dept of Radiation Oncology, Erasmus Medical Center, Rotterdam, The Netherlands 5. Dept of Pulmonary Diseases, Lievensberg Hospital, Bergen op Zoom, The Netherlands |
| Abstract: | Common complications of thoracic radiotherapy include esophagitis and radiation pneumonitis. However, it is important to be aware of uncommon post-radiotherapy complications such as bronchiolitis obliterans organizing pneumonia (BOOP). We report on two patients with carcinoma of the breast who developed an interstitial lung disease consistent with BOOP. BOOP responds to treatment with corticosteroids and the prognosis is generally good despite of the need for long-term administration of corticosteroids as relapses can occur during tapering of steroids. This report provides guidelines for the evaluation and treatment of patients with pulmonary infiltrates after radiotherapy. |
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