| 卵巢上皮性肿瘤雌激素受体、孕激素受体测定的临床意义 |
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| 引用本文： | 张哗,糜若然. 卵巢上皮性肿瘤雌激素受体、孕激素受体测定的临床意义[J]. 天津医药, 2000, 28(8): 456-468 |
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| 作者姓名： | 张哗 糜若然 |
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| 作者单位： | 天津医科大学总医院妇产科,300052 |
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| 摘 要： | 目的：探讨雌激素受体（ＥＲ）、孕激素受体（ＰＲ）在卵巢原发性上皮性肿瘤中的临床意义。方法：采用免疫组化法测定６７例恶性肿瘤、４４例良性肿瘤和１０例正常卵巢ＥＲ、ＰＲ状态。结果：ＥＲ、ＰＲ阳性率在恶性肿瘤分别为５８．２％、２６．９％，良性肿瘤分别为３６．４％、３１．６％，正常卵巢各为４０％、７０％。恶性肿瘤ＥＲ表达明显高于良性肿瘤及正常卵巢（Ｐ〈０．０５），而ＰＲ表达则较低（Ｐ〈０．０５）。经多因素
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| 关 键 词： | 卵巢肿瘤 预后 雌激素受体 孕激素受体 测定 |
Clinical Significance of Testing Estrogen and Progesterone Receptors in Patients with Ovarian Epithelial Tumor |
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| ZHANG Ye,MI Ruoran. Clinical Significance of Testing Estrogen and Progesterone Receptors in Patients with Ovarian Epithelial Tumor[J]. Tianjin Medical Journal, 2000, 28(8): 456-468 |
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| Authors: | ZHANG Ye MI Ruoran |
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| Affiliation: | ZHANG Ye,MI Ruoran Department of Obstetrics and Gynecology,Tianjin Medical University Hospital 300052 |
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| Abstract: | Objective:To probe the clinical significance of testing estrogen receptor (ER) and progesterone receptor (PR) in pa-tients with ovarian epithelial tumor. Methods:The immunohistochemical detection of ER and PR was performed in 67 cases of malignant tumor,44 cases of benign tumor and 10 cases of normal ovary. Results:The positive rates of ER and PR in ma-lignant tumor,benign tumor and normal ovary were 58.2% and 26.9% ,36.4% and 31.6% ,40.0% and 70.0% respec-tively . The ER expression in malignant tumor was obviously higher than that in benign tumor or normal ovary (P
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| Keywords: | ovarian neoplasms immunohistochemistry prognosis |
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