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| 儿童幽门螺杆菌感染中血清外泌体蛋白质组学作用研究进展 | |
| 引用本文： | 尧战勇,许春娣,颜凯,傅睿. 儿童幽门螺杆菌感染中血清外泌体蛋白质组学作用研究进展[J]. 中国处方药, 2020, 0(3): 30-32 |
| 作者姓名： | 尧战勇 许春娣 颜凯 傅睿 |
| 作者单位： | 南昌大学江西医学院;上海交通大学医学院附属瑞金医院北院儿内科;成都市双流区妇幼保健院;江西省儿童医院肾内科 |
| 基金项目： | 国家自然科学基金/面上项目(81570508)。 |
| 摘 要： | 外泌体(Exosome)的产生几乎与机体中的所有类型细胞相关,在多种体液中均能存在,如血液、尿液、唾液等,甚至有学者研究发现,外泌体在所含有的某些重要组分在不同病例条件下其存在的方式与扮演的角色也有所差异,尤其是在细菌组分传播中所发挥的作用更显突出。借此,笔者将从外泌体的研究背景、形成、分泌及其与幽门螺杆菌(Hp)的相互作用等方面进行综述研究,以期为小儿Hp感染患儿的临床诊治提供理论依据。 |
| 关 键 词： | 儿童 幽门螺杆菌感染 血清 外泌体 蛋白质组学 |
Progress in proteomics of serum exosomes in children with helicobacter pylori infection |
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| Affiliation: | (Jiangxi Medical College,Nanchang University,Nanchang 330006,China;Department of Pediatrics,Ruijin Hospital North,Shanghai Jiaotong University School of Medicine,Shanghai 201800,China;Chengdu Shuangliu District Maternal and Child Health Hospital,Chengdu 610200,China;Department of Nephrology,Jiangxi Provincial Children's Hospital,Nanchang 330006,China) |
| Abstract: | Exosome is related to almost all types of cells in the body.It can exist in many kinds of body fluids,such as blood,urine,saliva and so on.Some scholars have even found that the exosome contains some essential components in different cases and plays a role in their existence.Differences,especially in the transmission of bacterial components,play a more important role.In order to provide a theoretical basis for the clinical diagnosis and treatment of children with Hp infection,the author will review the background,formation,secretion of exosomes and in order to provide theoretical basis for clinical diagnosis and treatment of children with Hp infection. |
| Keywords: | Children Helicobacter pylori infection Serum Exosome Proteomics |
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