| 针刺镇痛与大鼠全脑cAMP和cGMP含量变化之间的关系 |
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| 引用本文： | 叶建红,刘永莉,孔庆玺.针刺镇痛与大鼠全脑cAMP和cGMP含量变化之间的关系[J].泸州医学院学报,2001,24(5):402-404. |
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| 作者姓名： | 叶建红 刘永莉 孔庆玺 |
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| 作者单位： | 1. 成都军区昆明总医院中医科
2. 昆明市第三人民医院, |
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| 摘 要： | 目的：探讨针刺镇痛与脑cAMP和cGMP含量变化之间的关系。方法：运用放射免疫分析法（RIA）测定大鼠电针前后，全脑组织中cAMP和cGMP含量的变化。结果：电针30min提高大鼠痛阈的同时，使全脑cAMP含量显著降低（P＜0．05）。结论：中枢环核苷酸可能参与针刺镇痛。
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| 关 键 词： | 电针 环磷酸腺苷 环磷酸鸟苷 放射免疫分析 针刺镇痛 |
| 文章编号： | 1000-2669(2001)05-0402-03 |
| 修稿时间： | 2001年6月10日 |
RELATIONSHIP BETWEEN ACUPUNCTURE ANALGESIA AND THE CONTENTS OF CAMP & CGMP IN WHOLE BRAIN OF RATS |
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| Ye Jianhong,et al.RELATIONSHIP BETWEEN ACUPUNCTURE ANALGESIA AND THE CONTENTS OF CAMP & CGMP IN WHOLE BRAIN OF RATS[J].Journal of Luzhou Medical College,2001,24(5):402-404. |
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| Authors: | Ye Jianhong |
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| Institution: | Ye Jianhong,et al Department of TCM,Kunming General Hospital,Chengdu Military Command,PLA |
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| Abstract: | Objective: To explore the relationship between acupuncture analgesia and the contents of cAMP & cGMP in the whole brain of rats. Methods: The contents of cAMP & cGMP rats before and after electroacupuncture(EA) were detected by radioimmunoassay (RIA). Results: The content of cAMP in the whole brain of rats is lowered remarkably (P<0.05) while the threshold of pain arises after EA for 30 minutes. Conclusion: The central cyclic nucleotides may probably participate in acupuncture analgesia. |
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| Keywords: | Electroacupuncture Cyclic AMP Cyclic GMP Radioimmunoassay (RIA) Acupuncture analgesia |
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