Long-term clinical effects of epalrestat, an aldose reductase inhibitor, on diabetic peripheral neuropathy: the 3-year, multicenter, comparative Aldose Reductase Inhibitor-Diabetes Complications Trial期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Long-term clinical effects of epalrestat, an aldose reductase inhibitor, on diabetic peripheral neuropathy: the 3-year, multicenter, comparative Aldose Reductase Inhibitor-Diabetes Complications Trial

Authors:	Hotta Nigishi Akanuma Yasuo Kawamori Ryuzo Matsuoka Kempei Oka Yoshitomo Shichiri Motoaki Toyota Takayoshi Nakashima Mitsuyoshi Yoshimura Isao Sakamoto Nobuo Shigeta Yukio

Affiliation:	Chubu Rosai Hospital, 1-10-6 Komei, Nagoya 455-8530, Japan. hotta@chubuh.rofuku.go.jp

Abstract:	OBJECTIVE: We sought to evaluate the long-term efficacy and safety of epalrestat, an aldose reductase inhibitor, on diabetic peripheral neuropathy. RESEARCH DESIGN AND METHODS: Subjects with diabetic neuropathy, median motor nerve conduction velocity (MNCV) >or=40 m/s, and HbA(1c)

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