The popularization and application of cold storage red blood cells or whole blood at ?80 °C of the Rh(D) negative patients in surgical operation |
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Authors: | Yu Zhongqing Hu Lihua Han Min Rao Shenzong Luo Chengwei |
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Institution: | (1) Department of Blood Transfusion, Xiehe Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430022 Wuhan |
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Abstract: | Summary The efficiency of cold storage red blood cells (CSRBC) or whole blood at −80 °C used in 27 Rh(D) negative patients during
surgical operation was reported. The Rh(D) negative patients received the transfusion of CSRBC or whole blood stored at −80
°C for 180 to 360 days. The changes in the indexes, such as blood TB, DB, K+, Na+, BUN, Cr, urine protein (URPO), UOB, Hb, HCT, serum total protein, relative to hemolytic reaction and blood volume before
and after transfusion were observed. The results showed that after transfusion of CSRBC or whole blood 27 cases were negative
for urine protein and UOB, and the levels of BUN and Cr were normal (P>0.05). Blood TB, DB, Hb, and HCT were increased, while pH, blood K+ and blood Na+ was normal with the difference being not significant before and after operation (P>0.05). Plasma protein was decreased, but there was no significant difference before and after operation (P>0.05). It was suggested that CSRBC or whole blood at −80 °C could be safely infused to the Rh(D) negative patients without
side effects during the surgical operation.
YU Zhongqing, male, born in 1957, Technician in Charge |
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Keywords: | Rh(D) negative patient − 80 °C cold storage red blood cells surgical operation hemolytic reaction |
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