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大剂量阿糖胞苷治疗儿童急性髓性白血病的发展现状
引用本文:胡静雯,于雅莲,黄家珍. 大剂量阿糖胞苷治疗儿童急性髓性白血病的发展现状[J]. 中国医药导报, 2011, 8(22): 8-9
作者姓名:胡静雯  于雅莲  黄家珍
作者单位:中国医科大学七年制临床医学,辽宁沈阳,110004
摘    要:
阿糖胞苷作为治疗儿童急性髓性白血病的化学治疗药物的主要药物之一,其作用机制得到深入研究。近年来,随着大剂量阿糖胞苷在急性髓性白血病化疗过程中的广泛应用,其高浓度依赖性毒副作用日益严重。如何选用最佳剂量及疗程是大剂量阿糖胞苷治疗儿童急性髓性白血病的关键问题。本文将对大剂量阿糖胞苷治疗儿童急性髓性白血病的发展现状作一综述。

关 键 词:急性髓性白血病  儿童  大剂量阿糖胞苷

Current situation of high-dose cytarabine in treatment of children with acute myeloid leukemia
HU Jingwen,YU Yalian,HUANG Jiazhen. Current situation of high-dose cytarabine in treatment of children with acute myeloid leukemia[J]. China Medical Herald, 2011, 8(22): 8-9
Authors:HU Jingwen  YU Yalian  HUANG Jiazhen
Affiliation:HU Jingwen,YU Yalian,HUANG Jiazhen China Medical University Clinical Medicine Department(Seven-years System),Liaoning Province,Shenyang 110004,China
Abstract:
Cytarabine is used as one of the main durgs to treat the acute myeloid leukemia and its mechanism of action has been investigated further.The superiority of high-dose cytarabine has been thought highly in the recent years,but the adverse effects can not be avoided.This paper will review the current situation of high-dose cytarabine in treatment of children with acute myeloid leukemia.
Keywords:Acute myeloid leukemia  Childhood  High-dose cytarabine  
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