| 赛霉安阴道栓对家兔阴道粘膜刺激试验 |
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| 引用本文： | 刘用国,王江融,李鸣.赛霉安阴道栓对家兔阴道粘膜刺激试验[J].海峡药学,2007,19(4):27-29. |
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| 作者姓名： | 刘用国 王江融 李鸣 |
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| 作者单位： | 福建省药品检验所,福州,3500010 |
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| 摘 要： | 目的 观察赛霉安阴道栓对阴道粘膜的刺激反应.方法 以家兔阴道每日持续给药4 h,每日1.0 g/只,连续给药10日,同时设赋型剂对照组,观察对阴道的刺激反应.结果 经肉眼临床观察未见明显水肿、糜烂、出血、溃疡等病理改变,组织病理学镜检赛霉安阴道栓对家兔阴道粘膜刺激反应程度为无刺激.结论 赛霉安阴道栓对阴道粘膜无刺激性.
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| 关 键 词： | 赛霉安阴道栓 阴道粘膜刺激 |
| 文章编号： | 1006-3765（2007）04-0027-03 |
Vaginal mucosa irritation test of SaiMeiAn vaginal suppositories on rabbits |
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| LIU Yong-guo,WANG Jiang-rong,LI-Ming.Vaginal mucosa irritation test of SaiMeiAn vaginal suppositories on rabbits[J].Strait Pharmaceutical Journal,2007,19(4):27-29. |
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| Authors: | LIU Yong-guo WANG Jiang-rong LI-Ming |
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| Institution: | Fujian Institute for Drug Control, Fuzhou 350001, China |
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| Abstract: | OBJECTIVE To detect the vaginal mucosa irritation of SaiMeiAn vaginal suppositories. METHODS SaiMeiAn vaginal suppositories was continuously given to vagina of rabbits 4 hours a day,the dose were 1. 0g per rabbit, givng ten days in continually. Meantime the prcipients control group were given. The irritation reactions on vagina tissues was observed. RESULTS There was no significant change in vagina tissues such as edema, blood, fester, ulcer. The tissues checked by microscope indicated that SaiMeiAn on vaginal suppositories has no irritation on vaginal mucosa. CONCLUSION The SaiMeiAn vaginal suppositories has no vaginal mucosa irritation on rabbits. |
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| Keywords: | SaiMeiAn vaginal suppositories viginal mucosa irritation |
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